NASHVILLE, Tenn. -- The Titans get the big spotlight in Week 2 of the NFL season, playing the Bills on Monday Night Football in Orchard Park, N.Y.
The game will be the opener of a doubleheader, kicking off at 6:15 pm CT on ESPN with the Vikings at Eagles starting on ABC at 7:30 on ABC.
Pool photo/ Tennessee Titans
As of Monday morning. Buffalo is the AFC favorite at +350 and the Super Bowl favorite at +650 at Fan Duel. The Titans are ninth (+1500) and 15th (+3000). [Unlocked]
The Titans lost 13-12 at Buffalo in 2018 and 14-7 in Nashville in 2019.
But the last two meetings of rosters much closer to the ones that will square off on Sept. 19 have gone the Titans’ direction.
On Tuesday, Oct. 13, 2020, after the Titans' long layoff due to a Covid 19 outbreak, Tennessee came back from one practice in 16 days and stunned Buffalo with a 42-16 win at Nissan Stadium.
And on Oct. 18, 2021, a Josh Allen slip and a big play from Jeffery Simmons on a fourth-and-1 from the Titans’ 3 ended the Bills' hopes in a 34-31 Tennessee win.
The Bills drafted cornerback Kaiir Elam and running back James Cook, a good receiver, with their top two picks. In free agency, they continued to work on their pass rush by adding Von Miller and Shaq Lawson.
The running game and pass protection will have new options on the offensive line with a couple of former Titans: Rodger Saffold and David Quessenberry, while a third former player from Tennessee, DaQuan Jones, will look to bolster the run defense.
The Titans are also minus A.J. Brown and Julio Jones but have added veteran Robert Woods (who is recovering from ACL repair but should be ready for this game), Austin Hooper and Treylon Burks.
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